:root{color-scheme:dark;--bg:#071f29;--panel:#0e303b;--ink:#edf8f2;--muted:#b2ccd0;--mint:#a6efd0}*{box-sizing:border-box}body{margin:0;background:var(--bg);color:var(--ink);font:15px/1.6 system-ui,sans-serif}header{padding:18px 28px;border-bottom:1px solid #36525a;display:flex;justify-content:space-between;align-items:center;gap:20px;flex-wrap:wrap}.brand{display:flex;align-items:center;gap:12px;font-size:21px;font-weight:700;text-decoration:none}.brand span{font-size:13px;color:var(--muted);font-weight:400}a{color:var(--mint)}nav,.row,.controls{display:flex;gap:10px;align-items:center;flex-wrap:wrap}button,select,input{font:inherit}button,select{border:1px solid #42616b;border-radius:10px;background:#153945;color:var(--ink);padding:10px 14px;cursor:pointer}button:hover{background:#275765}button:disabled{opacity:.4;cursor:default}button:focus-visible,a:focus-visible,input:focus-visible,select:focus-visible,summary:focus-visible{outline:3px solid #f5cb79;outline-offset:3px}main{max-width:1600px;margin:auto;padding:30px}.eyebrow{color:var(--mint);text-transform:uppercase;letter-spacing:.14em;font-size:11px}h1{font-size:clamp(36px,5vw,65px);line-height:1.1;margin:20px 0}h2{line-height:1.2}h3{font-size:14px}.lead{font-size:20px;max-width:680px}.notice{max-width:900px;padding:16px;border-left:3px solid #f5cb79;background:#14323b;color:var(--muted)}#search{display:block;width:min(600px,100%);background:#112e39;color:white;border:1px solid #45616b;border-radius:10px;padding:12px;margin:8px 0 28px}#cards{display:grid;grid-template-columns:repeat(auto-fit,minmax(260px,1fr));gap:18px}.card{background:var(--panel);border:1px solid #34545d;border-radius:18px;padding:24px;display:flex;flex-direction:column;align-items:start;gap:10px}.card h2{margin:0}.card p{margin:0;color:var(--muted)}.card a,.card button{margin-top:auto}.card small{color:#efd49f}#experience{display:grid;grid-template-columns:300px minmax(0,1fr);gap:28px}aside{padding:20px;border-radius:18px;background:var(--panel);align-self:start}aside h1{font-size:32px}aside p{font-size:13px}aside select{width:100%;margin:8px 0 12px}aside details{border-top:1px solid #34545d;padding:14px 0}summary{cursor:pointer;font-weight:600}#connections{display:grid;gap:8px;margin-top:12px}#sources a{display:block;margin:8px 0;overflow-wrap:anywhere}article{min-width:0}.scene-heading{min-height:90px;padding:0 10px}.scene-heading h2{margin:4px 0;font-size:24px}.scene-heading small{color:var(--muted)}#viewport{height:clamp(260px,43vh,540px);position:relative;border-radius:18px;overflow:hidden;background:#05212a;border:1px solid #34545d}canvas{display:block;width:100%;height:100%;touch-action:none}.camera{position:absolute;right:10px;bottom:10px;display:flex;gap:4px}.camera button{padding:6px 12px;background:#123742e8}.legend{display:grid;grid-template-columns:1fr 1fr;gap:18px;padding:10px 16px}.legend h3{color:#78dbed}.legend>div+div h3{color:#ffb095}.legend ol{padding-left:24px;margin:0;font-size:13px;columns:2}.caption{background:var(--panel);padding:15px 22px;border-radius:14px;min-height:160px}.caption p{margin:5px 0}#subtitle{font-size:18px}#detail{color:var(--muted);font-size:14px}#energy{font-size:12px;color:#f5d18f}.controls{padding:15px 0}.controls label{font-size:12px;display:flex;align-items:center;gap:6px}.timeline{width:100%}.timeline input{flex:1;accent-color:var(--mint)}#webgl-error{position:absolute;inset:20px;background:var(--panel);padding:20px}dialog{max-width:700px;width:calc(100% - 24px);max-height:90vh;overflow:auto;background:#eaf4ee;color:#16373d;border:0;border-radius:18px;padding:25px}dialog::backdrop{background:#00151dcc}dialog fieldset{margin:18px 0;border:1px solid #8ba7a2;border-radius:12px}dialog label{display:block;padding:8px}dialog .feedback{background:#cce7da;padding:10px}[hidden]{display:none!important}@media(max-width:850px){main{padding:16px}#experience{grid-template-columns:1fr}aside h1{font-size:28px}aside{padding:16px}header{padding:12px}.brand span{display:none}#viewport{height:340px}.legend ol{columns:1}.controls button{min-height:44px}#experience{gap:16px}}@media(prefers-reduced-motion:reduce){*{scroll-behavior:auto}}

/* Illustrated catalog: real controls, decorative category artwork. */
#catalog h1{font-size:clamp(30px,4vw,48px)}#catalog .lead{max-width:900px}#category-filters{display:flex;flex-wrap:wrap;gap:10px}#category-filters button[aria-pressed=true]{background:#a6efd0;color:#071f29;border-color:#a6efd0}#catalog-count{color:var(--muted);font-size:13px}.pathway-art{object-fit:contain;align-self:flex-end;max-width:100%;height:100px}.card{background:linear-gradient(135deg,#103842,#082832);border-color:#29616d;border-radius:14px;gap:12px}.card h2{font-size:21px}.card button,.card a{min-height:44px}.card a{display:flex;align-items:center}#cards{grid-template-columns:repeat(auto-fit,minmax(245px,1fr))}#search{margin-bottom:16px} @media(max-width:500px){#cards{grid-template-columns:1fr}.pathway-art{height:80px}.card{padding:20px}}

/* Atomic models use element colors rather than input/output colors. */
body.gng .legend h3,body.gng .legend>div+div h3{color:#49347A} .atom-key{font-size:12px;color:#49347A;padding:8px 12px;background:#e4d8f5;border-radius:10px}

body.gng #viewport{height:clamp(340px,50vh,600px);box-shadow:inset 0 0 50px #e8dcff44}body.gng .atom-key{line-height:1.65} @media(max-width:700px){body.gng #viewport{height:350px}}

/* Ordem de comandos alinhada à experiência da glicólise. */
#experience .row{display:grid;grid-template-columns:1fr 1fr;gap:10px;margin:12px 0 20px}
#experience .row button{min-height:44px;white-space:nowrap}
#experience .controls{display:flex;align-items:center;gap:8px;padding:12px 14px;margin-top:12px;background:#EDE4FC;border:1px solid #CFBDF0;border-radius:16px}
#experience .controls button{min-height:42px;font-size:12px;white-space:nowrap;padding:9px 12px}
#experience .controls label{font-size:11px;gap:6px;white-space:nowrap}
#experience .controls select{width:70px;padding:9px}
#experience .controls .timeline{display:flex;flex-basis:100%;gap:12px;padding-top:6px}
#experience .controls .timeline input{width:100%;min-width:100px;min-height:22px}
#experience .camera{display:flex;gap:5px;background:#F4EEFFdd;padding:6px;border:1px solid #CFBDF0;border-radius:14px;bottom:10px;right:10px}
#experience .camera button{min-height:38px;min-width:36px;padding:6px 10px}
#experience .legend{padding:10px 14px;border:1px solid #ded0f3;border-radius:12px;margin:10px 0;gap:20px}
#experience .legend h3{margin:0 0 6px}#experience .legend ol{columns:1;margin:0;padding-left:22px}
#experience .representation-notes{margin:8px 0;color:#5C4782;font-size:12px}
#experience .representation-notes summary{padding:6px 4px}
#experience .representation-notes .atom-key{margin:5px 0}
#experience .caption{min-height:120px;padding:14px 18px}
@media(min-width:1100px){#experience .controls .timeline{flex:1 1 170px;padding:0}}
@media(max-width:700px){#experience .controls{gap:8px;padding:10px}#experience .controls button{flex:1 1 auto}#experience .controls .timeline{flex-basis:100%}#experience .camera button{padding:6px;min-width:32px}}

/* Mesmo painel de trabalho da glicólise: lateral, cena, resumo e barra inferior. */
.reaction-equation{padding:14px;border:1px solid #B99DDF;border-radius:12px;background:#F3EDFD;color:#34205D;font-size:14px;font-weight:600;line-height:1.6;margin:16px 0}
#experience .scene-meta{display:flex;justify-content:space-between;align-items:center;gap:12px;min-width:0}
#experience .scene-meta .legend{flex:1;border:0;margin:0;padding:0 10px;min-width:0;gap:12px}
#experience .scene-meta .legend h3{font-size:13px;margin:0 0 3px}
#experience .scene-meta .legend ol{display:flex;flex-wrap:wrap;gap:2px 14px;list-style:none;padding:0;font-size:11px;line-height:1.4}
#experience .scene-meta .camera{position:static;flex:none;margin:0}
@media(min-width:851px) and (min-height:600px){
 body:has(#experience:not([hidden])){overflow:hidden}
 body:has(#experience:not([hidden]))>header{position:fixed;top:0;left:0;right:0;height:76px;padding:12px 24px;z-index:4;box-sizing:border-box}
 #experience{display:block}
 #experience>aside{position:fixed;left:16px;top:90px;bottom:16px;width:300px;overflow:auto;padding:22px;border:1px solid #CFBDF0;box-sizing:border-box}
 #experience>aside h1{font-size:30px;margin:20px 0;line-height:1.17}
 #experience>aside #tissue{font-size:12px;line-height:1.6}
 #experience>article{position:fixed;left:332px;right:16px;top:90px;bottom:12px;display:grid;grid-template-rows:72px minmax(140px,1fr) 66px 112px 90px;gap:10px;min-height:0}
 #experience .scene-heading{min-height:0;margin:0;padding:0 12px;border-left:5px solid #29ADC4;overflow:auto}
 #experience .scene-heading .eyebrow{margin:0 0 4px;font-size:10px}
 #experience .scene-heading h2{font-size:28px;margin:3px 0}
 #experience .scene-heading small{font-size:10px;line-height:1.3;display:block}
 #experience #viewport,body.gng #experience #viewport{height:100%;min-height:0;width:100%;margin:0}
 #experience .caption{height:112px;min-height:0;padding:10px 16px;overflow:auto;box-sizing:border-box}
 #experience .caption #phase{font-size:11px;margin:0 0 4px}
 #experience .caption #subtitle{font-size:14px;line-height:1.45;margin:4px 0}
 #experience .caption #detail{font-size:12px;line-height:1.4;margin:4px 0}
 #experience .caption #energy{font-size:11px;margin:4px 0}
 #experience .controls{margin:0;padding:9px 12px;gap:6px;align-content:center;box-sizing:border-box;overflow:auto;min-height:0}
 #experience .controls button{min-height:34px;font-size:11px;padding:7px 9px}
 #experience .controls label{font-size:10px}
 #experience .controls select{padding:6px;width:64px}
 #experience .controls .timeline{flex:1 1 150px;padding:0}
 #experience .controls .timeline input{min-height:18px}
 #experience .representation-notes{margin-top:14px}
}
@media(min-width:851px) and (max-width:1100px) and (min-height:600px){#experience>aside{width:245px;padding:16px}#experience>article{left:277px;grid-template-rows:72px minmax(140px,1fr) 74px 112px 100px}#experience .scene-meta .camera button{min-width:28px;padding:5px;font-size:10px}#experience .scene-meta .legend ol{font-size:10px}}
@media(max-width:850px){#experience .scene-meta{flex-wrap:wrap}#experience .scene-meta .camera{margin-left:auto}#experience .scene-meta .legend{flex-basis:100%;padding:8px}#experience .scene-heading{overflow-wrap:anywhere}}

/* Rolagem explícita: informações expandidas nunca ficam inacessíveis. */
#experience>aside{scrollbar-width:auto;scrollbar-color:#9474CD #E9DFF8;scrollbar-gutter:stable;overscroll-behavior:contain}
#experience>aside::-webkit-scrollbar{width:12px}
#experience>aside::-webkit-scrollbar-track{background:#E9DFF8;border-radius:10px}
#experience>aside::-webkit-scrollbar-thumb{background:#9474CD;border:3px solid #E9DFF8;border-radius:10px}
#experience>aside::-webkit-scrollbar-thumb:hover{background:#67449E}
@media(min-width:851px) and (min-height:600px){
 #experience>aside{height:calc(100dvh - 106px);max-height:calc(100dvh - 106px);min-height:0;overflow-y:scroll!important;overflow-x:hidden;bottom:auto;padding-bottom:30px}
 #experience>aside details{overflow-wrap:anywhere}
 #experience>article .caption{overflow-y:auto;scrollbar-width:auto;scrollbar-color:#9474CD #E9DFF8;scrollbar-gutter:stable}
}
@media(max-width:850px),(max-height:599px){body:has(#experience:not([hidden])){overflow-y:auto!important}#experience>aside{overflow:visible;max-height:none;height:auto}}

/* Dar prioridade à reação e manter comandos acessíveis. */
@media(min-width:851px) and (min-height:600px){
 #experience>article{grid-template-rows:62px minmax(180px,1fr) 54px 88px 78px;gap:8px}
 #experience .scene-heading h2{font-size:26px}
 #experience .caption{height:88px;padding:9px 14px}
 #experience .scene-meta .legend{gap:8px}
 #experience .scene-meta .camera{padding:4px}
 #experience .controls{padding:7px 10px}
}
@media(min-width:851px) and (max-width:1100px) and (min-height:600px){#experience>article{grid-template-rows:62px minmax(170px,1fr) 60px 88px 90px}}
@media(max-width:850px){body.gng #experience #viewport{height:440px;min-height:340px}}

/* Três referências espaciais legíveis, sem rótulos minúsculos dentro do 3D. */
#transport-regions{position:absolute;left:16px;right:16px;top:12px;z-index:2;display:flex;justify-content:space-between;gap:12px;pointer-events:none;color:#34205D;font-size:14px;font-weight:600}
#transport-regions span{background:#F4EEFFed;padding:6px 12px;border-radius:8px;text-align:center}
#transport-regions span:nth-child(2){font-size:12px;font-weight:400}
@media(max-width:700px){#transport-regions{left:8px;right:8px;font-size:12px;gap:5px}#transport-regions span{padding:5px 7px}#transport-regions span:nth-child(2){font-size:10px}}

#enolase-label{position:absolute;top:12px;left:16px;right:16px;z-index:2;margin:0;padding:9px 14px;background:#F4EEFFee;border:1px solid #D0C1F4;border-radius:10px;color:#34205D;font:600 16px/1.5 'Segoe UI',sans-serif;text-align:center;pointer-events:none}
@media(max-width:700px){#enolase-label{font-size:14px;left:8px;right:8px;padding:8px}}

/* A equação fica na explicação, nunca sobre as moléculas. */
#experience .caption #enolase-label{position:static;margin:0 0 6px;padding:0;border:0;background:transparent;color:#34205D;font-size:14px;line-height:1.4;text-align:left;pointer-events:auto}